How did francis crick discover the structure of DNA?
Watson and Crick used stick-and-ball models to test their ideas on the possible structure of DNA. Other scientists used experimental methods instead. Among them were Rosalind Franklin and Maurice Wilkins, who were using X-ray diffraction to understand the physical structure of the DNA molecule. When you shine X-rays on any kind of crystal – and some biological molecules, such as DNA, can form crystals if treated in certain ways – the invisible rays bounce off the sample. The rays then create complex patterns on photographic film. By looking at the patterns, it is possible to figure out important clues about the structures that make up the crystal.