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How do cervical cancer and its precursor lesions develop?

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How do cervical cancer and its precursor lesions develop?

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There are about 450,000 new cases of cervical cancer worldwide each year. Cervical cancer develops gradually over a long period of time through a sequence of precursor lesions. Persistent infections with high-risk human papillomaviruses (HR-HPV) have been demonstrated to be causatively involved in the pathogenesis of cervical cancer and its precursor lesions.

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