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How do I know which mechanism to use in response to a specific Funding Opportunity (FO) or for investigator-initiated applications?

April 26, 2017applications FO funding investigator-initiated mechanism opportunity Response

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How do I know which mechanism to use in response to a specific Funding Opportunity (FO) or for investigator-initiated applications?

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There are several strategies to use in deciding which research or training mechanism to use. First, here are some useful definitions and background information. The mechanism, or activity code designates a particular type of grant. For example, the R03 mechanism is a small grant for two years of pilot work that is not renewable. The R01 mechanism is the standard NIH grant for larger research projects that are based on pilot studies that yielded significant and published results. In addition to these two mechanisms, others include the R15, R21, F31, F32, K01, K23, R43 (small business), and so on. Note that there are many funding mechanisms at NIH but each Institute supports its own subset of mechanisms. See the IC (Institute or Center) website for specific mechanisms supported. In addition, there are NIH Roadmap initiatives supported by all ICs. Here are strategies to use in deciding the appropriate mechanism for an application.