How do people inherit NF2?
NF2 is inherited in an autosomal dominant pattern which means only one copy of the altered gene is necessary to cause the disorder. In about half of all cases, an affected person has one affected parent. The other half result from new mutations which means that neither parent is affected. All individuals have a 50% chance of passing the disorder on to their children. NF2 affects both genders equally and is located on the 22 chromosome.