How do scientists know that chlorine is responsible for stratospheric ozone depletion?
In 1987, NASA and a group of scientists flew a modified U-2 spy plane (now called the ER-2) into the ozone hole over Antarctica. During this flight they found that as they entered the hole chlorine compounds went up at exactly the same time that ozone decreased. This measurement was proof that chlorine really was responsible for the ozone hole. (For more read: , Anderson, J.G., W.H. Brune, M.H. Proffett, 1989, Journal of Geophysical Research, vol 94, PP 11465-11479. and Anderson, J.G. D.W. Toohey, W.H. Brune, 1991, Science, vol 251, pp39-46.