How do selective serotonin reuptake inhibitors work?
Mounting research shows that people with depression and anxiety have an imbalance of the brain’s neurotransmitters. These are chemicals in the brain that allow nerve cells to communicate. One of these neurotransmitters is serotonin. An imbalance in serotonin may be an important factor in the development of depression and anxiety. Serotonin is released from one nerve cell and passed to the next. In the process, some of the serotonin released is reabsorbed by the first nerve cell. SSRIs, like Lexapro, block the reabsorption of serotonin into the first nerve cell. It is this blocking action that causes an increased amount of serotonin to become available at the next nerve cell. This is how SSRIs affect the balance of serotonin in the brain.