How does a person get pancreatic cancer?
There are risk factor that can make a person more likely to get this disease. Some risk affect DNA of cells in the pancreas. Some people inherit genes from their parents that raise their risk of pancreatic cancer. Smoking is number factor for pancreatic disease/cancer. Other gene changes can also be found in pancreatic cancers, although often it’s not clear what has caused these changes.
No one knows what the major causes for pancreatic cancer is but they do know some of the various factors that can make you more prone to getting pancreatic cancer. There are three catagories of risk factors, General, Lifestyle, and Genetic.
General:
- Age (almost 90% of all pancreatic cancers are found in people age 55 and older)
- Gender: For an unknown reason, men are somewhat more likely to develop pancreatic cancer than are women.
- Obesity
- Diabetes
- Chronic pancreatitis
- Cirrhosis of the liver
- Helicobacter pylori (H. pylori) infection
Lifestyle:
- Smoking cigarettes: Almost a third (20-30 percent) of all pancreatic cancers are linked to smoking cigarettes. Carcinogens (cancer-causing chemicals) found in tobacco products may damage the pancreas, and smoking may add to the risks associated with other conditions, like long-term inflammation of the pancreas (chronic pancreatitis). Likewise, the risk of diabetes and obesity may also be greater if an individual smokes.
Genetic:
About 10 percent of pancreatic cancers are thought to be related to genetic factors, meaning an inherited gene mutation is passed on from parents to their children. Although these genetic conditions do not directly cause pancreatic cancer, they may increase your risks for developing the disease.
The following genetic mutations are considered risk factors for pancreatic cancer:
- Mutations in the gene BRCA2 (hereditary breast and ovarian cancer syndrome)
- Mutations in the gene p16 (familial melanoma)
- Mutations in the gene PRSS1 (familial pancreatitis)
- Mutations in the gene NF1 (neurofibromatosis, type 1)
Other inherited syndromes that may be linked to pancreatic cancer include:
- Lynch Syndrome
- Peutz-Jeghers Syndrome (PJS)
- Von Hippel-Lindau Syndrome (VHL)
- MEN1 (multiple endocrine neoplasia type 1) syndrome: A rare genetic disorder that may be a risk factor for malignant islet cell tumors
To learn more about Pancreatic Cancer just visit the link below!
https://www.cancercenter.com/pancreatic-cancer/risk-factors/
Many risk factors for pancreaic cancer has been involved; genetics has apparently plays a rol. About 10% of people that have had a relative with this type of tumor, had developed one too. Though, it has not been discovered a pancreatic cancer gene.
Diabetes can be involved in pancreatic cancer. also inflammatory activity and fibrosis, caused by chronic pancratitis is an important risk factor. Alcohol is a toxic that can cause chronic pancreatitis, also biliar ducts and gallbladder stones.
Smoking has been found as an important risk factor for pc. it has been stablished as a major risk factor. About one fourth of all deaths caused for pancreatic cancer are linked to tobacco use. The average age for diagnosis of pc is 15 years earlier in smokers than in no smokers.
Scientists don’t know exactly what causes most pancreatic cancers, but they have found several risk factors that can make a person more likely to get this disease. Some of these risk factors affect the DNA of cells in the pancreas, which can result in abnormal cell growth and may cause tumors to form.
Some of the risk factors they one can get pancreatic cancer include: Cigarette smoking: Cigarette smoking doubles the risk of pancreatic cancer. In fact, some scientists have estimated that one in four, or one in five cases of pancreatic cancer are caused by smoking cigarettes. Smoking is also associated with early age at diagnosi
