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How does a person get pancreatic cancer?

Health
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Frank Bell70 Posted

How does a person get pancreatic cancer?

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Brent Foust

There are various causes of developing pancreatic cancer. Chronic inflammation of pancreas, diabetes, family history of pancreatic cancer, smoking, obesity, and advanced age can increase your risk of pancreatic cancer.

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John Wakler

Most of the cancers have no early signs. In the case of pancreatic cancer, It is always difficult to detect this type of cancer early. Uncontrollable growth of cells in your pancreas that develop mutations in their DNA. This results in an uncontrolable growth of cells.

Read more about cancer causes:- http://www.pillsuppliers.com/blog/signs-and-symptoms-of-cancer/

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Pancreatic cancer occurs when cells in your pancreas develop mutations in their DNA. These mutations cause cells to grow uncontrollably and to continue living after normal cells would die. These accumulating cells can form a tumor. Untreated pancreatic cancer spreads to nearby organs and blood vessels.

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“Diseases & Conditions: Pancreatic cancer”
CAUSES
It’s not clear what causes pancreatic cancer in most cases. Doctors have identified factors, such as smoking, that increase your risk of developing the disease.

How pancreatic cancer forms
Pancreatic cancer occurs when cells in your pancreas develop mutations in their DNA. These mutations cause cells to grow uncontrollably and to continue living after normal cells would die. These accumulating cells can form a tumor. Untreated pancreatic cancer spreads to nearby organs and blood vessels.

Most pancreatic cancer begins in the cells that line the ducts of the pancreas. This type of cancer is called pancreatic adenocarcinoma or pancreatic exocrine cancer. Rarely, cancer can form in the hormone-producing cells or the neuroendocrine cells of the pancreas. These types of cancer are called islet cell tumors, pancreatic endocrine cancer and pancreatic neuroendocrine tumors.

RISK FACTORS
Factors that may increase your risk of pancreatic cancer include:
Chronic inflammation of the pancreas (pancreatitis)
Diabetes
Family history of genetic syndromes that can increase cancer risk, including a BRCA2 gene mutation, Lynch syndrome and familial atypical mole-malignant melanoma (FAMMM) syndrome
Family history of pancreatic cancer
Smoking
Obesity
Older age, as most people are diagnosed after age 65

A large study demonstrated that the combination of smoking, long-standing diabetes and a poor diet increases the risk of pancreatic cancer beyond the risk of any one of these factors alone.」 (emphases added)
https://www.mayoclinic.org/diseases-conditions/pancreatic-cancer/symptoms-causes/syc-20355421

“Pancreatic cancer: Pancreatic Cancer Causes and Risk Factors”
「Pancreatic Cancer Causes Still Unknown
Pancreatic cancer develops when a cell in the pancreas acquires damage to its DNA that causes it to behave and multiply abnormally. A single cancer cell grows and divides rapidly, becoming a tumor that does not respect normal boundaries in the body. Eventually, cells from the tumor travel elsewhere in the body (metastasize) through the blood or lymphatic system.

No one knows exactly how the process of DNA damage leading to pancreatic cancer occurs. Analyzing pancreatic cancers removed by surgery shows certain mutations that occur in nearly all cases, and others that vary between people.

Some of these mutations occur randomly. Others occur in response to things we do or experience in the environment. Some mutations may be inherited. When enough mutations accumulate, a cell becomes malignant and a tumor begins to grow.」
https://www.webmd.com/cancer/pancreatic-cancer/causes-pancreatic-cancer

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It’s not clear what causes pancreatic cancer in most cases. Factors, such as smoking, that increase your risk of developing the disease.

Pancreatic cancer occurs when cells in your pancreas develop mutations in their DNA. 2  types of mutation are found : 1.Inherited gene mutations

2.Acquired gene mutations

These mutations cause cells to grow uncontrollably and to continue living after normal cells would die. These accumulating cells can form a tumor. Untreated pancreatic cancer spreads to nearby organs and blood vessels.

Most pancreatic cancer begins in the cells that line the ducts of the pancreas. This type of cancer is called pancreatic adenocarcinoma or pancreatic exocrine cancer. Rarely, cancer can form in the hormone-producing cells or the neuroendocrine cells of the pancreas. These types of cancer are called islet cell tumors, pancreatic endocrine cancer and pancreatic neuroendocrine tumors.

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