How does purified HupA influence Alzheimer’s disease?
Acetylcholine is a neurotransmitter critical for cognitive processing, memory, arousal, and attention. Gradual loss of mental clarity is associated with both diminishing acetylcholine synthesis and rapid degradation of this neurotransmitter by the enzyme acetylcholinesterase. Abundant research suggests that HupA exerts a slow reversible inhibition of acetylcholinesterase, thus preserving acetylcholine and leading to the alleviation of many of the symptoms and progression of AD.