How does the degree of carotid stenosis affect the accuracy and interobserver variability of magnetic resonance angiography?
OBJECTIVES: The accuracy of magnetic resonance angiography (MRA) was determined in patients with recently symptomatic tight (80%-99%) carotid stenosis (on Doppler ultrasound), and the effect of stenosis severity on the accuracy and interobserver variability of MRA was studied. METHODS: Forty four consecutive patients undergoing intra-arterial angiography (IAA) before carotid endarterectomy were prospectively studied, in two centres with identical MR scanners and sequences. All patients had undergone Doppler ultrasound, showing a 70% or worse carotid stenosis on the symptomatic side. MRA and IAA were done during the same admission. The MRA films were each independently and blindly read for percentage stenosis (signal gap if present) by four observers. The IA angiograms were read separately by one observer, blind to symptoms, and Doppler and MRA results. RESULTS: Signal gaps on MRA were seen in stenoses ranging from 67% to 99% on intra-arterial angiography. Magnetic resonance angiograms
