How exactly did Anna Nicole Smith die???
After a seven week investigation led by Broward County Medical Examiner and Forensic Pathologist Dr. Joshua Perper in combination with the Seminole police and several independent forensic pathologists and toxicologists, Dr. Perper announced that Smith died of “combined drug intoxication” with the sleeping medication chloral hydrate as the “major component.”No illegal drugs were found in her system. The official report states that her death was not considered to be due to homicide, suicide, or natural causes.Ultimately her death was ruled an accidental drug overdose of the sedative chloral hydrate that became increasingly lethal when combined with other prescription drugs in her system, specifically 4 benzodiazepines: Klonopin (Clonazepam), Ativan (Lorazepam), Serax (Oxazepam), and Valium (Diazepam). Furthermore, she had taken Benadryl (Diphenhydramine) and Topamax (Toprimate), an anticonvulsant GABA agonist, which likely contributed to the sedative effect of chloral hydrate and the ben