How is Nebido® used?
The injections must be administered very slowly (over 1 to 2 minutes). It is possible and advisable to use a 22 G injection needle. Care should be taken to inject Nebido® deeply into the gluteal muscle following the usual precautions for intramuscular administration. Special care must be given to avoid intravasal injection. The content of an ampoule has to be injected intramuscularly immediately after opening the ampoule. Pulmonary microembolism of oily solutions can in rare cases lead to signs and symptoms such as cough, dyspnea, malaise, hyperhidrosis, chest pain, dizziness, paresthesia, or syncope. These reactions may occur during or immediately after the injections and are reversible. This is not specific for Nebido® and has been described for injections of testosterone in oily solutions in general.3 This can usually be avoided by injecting the solution very slowly and by making sure that the injection is strictly intramuscular.
