How is opioid addiction different from dependence or tolerance?
Many of the concerns regarding opioid use originate from misconceptions or confusion regarding the terminology describing the risks of addiction, tolerance, and dependence. Numerous authorities – including the American Academy of Pain Medicine, American Pain Society, and the American Society of Addiction Medicine – have addressed these concerns. An appreciation of more concise definitions can help dispel misunderstandings, which otherwise might lead to inadequate pain management therapy. Addiction (Substance Dependence) – is a disorder in which patients exhibit compulsive use of the drug, cravings, and loss of control (use of the drug continues despite harm to themselves or to others). Addiction is not a pharmacological side effect but rather a cluster of behavioral symptoms. While patients with a history of substance abuse may be at higher risk for developing addiction to opioids, the risk for most patients is very small. A commonly used reference from the American Psychiatric Associa
