How long do facial fillers like Restylane, Juvederm, Radiesse and Sculptra last?
Each of these fillers performs differently in each patient. Generally speaking, Restylane minimizes wrinkles in laugh lines and the upper lip area for up to six months. Juvederm can last from six months to a year. Radiesse is particularly effective in laugh lines and the cheekbone area and can last up to one year. Sculptra tends to last up to two years. With all fillers (except Sculptra), patients notice results after one treatment. In the case of Sculptra, the filler builds up slowly over a period of one to six months and requires three or four treatments one month apart.