How long does it take Amaryl to take effect?

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It can take up to 6 months for oral medications to lower your blood sugars to a normal level (metformin included) Two weeks is really pushing it. It is not uncommon for the doctor to change the dosage or even the medication while you are trying to get your disease under control. It can even take awhile to get the right dosage of insulin if you take that. It took me about 3 months before my doctor finally got the dosage of my long lasting insulin where it really helped me. My fast acting is a different story, that adjusts from meal to meal sometimes. Be patient, and keep in close contact with your doctor. Watch your diet, learn to count carbs and keep your meals at 45 grams of carbs. In between meal snacks can be 15 grams of carbs each. more
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