How long should I take clomiphene citrate?
It is usually very reasonable to take this medication for four to six months as long as it is stimulating ovulation. Most of the pregnancies achieved with clomiphene citrate are seen in this time period. Other oral medications for ovulation induction: Tamoxifen: a drug similar to clomiphene citrate in its actions. Letrozole (Femara): a drug that acts by a different mechanism than clomiphene citrate (it inhibits estrogen formation temporarily) and can work to induce ovulation. This drug is not FDA-approved for this purpose. Metformin: This drug can lower insulin levels in women with PCOS and, when used alone, has only modest effect in increasing ovulation. Recent studies of a large population of women with PCOS have shown that the combination of metformin and clomiphene citrate was no more effective than clomiphene citrate alone. Nevertheless, there may be some women who are not ovulating on clomiphene citrate alone who will ovulate in response to the combination of these drugs. Injecta
