How may pyruvate benefit people in weight-loss program?
Researchers from The University of Texas at Austin noticed that infusion of pyruvate and dihydroxyacetone directly into the blood produced strong metabolic effects. When chronically fed to animals as part of their diet, pyruvate plus dihydroxyacetone reduce the rate of weight gain and body fat content during growth. These alterations in growth pattern appear to be the result of an increased loss of calories as heat at the expense of storage of lipid.  In addition to the above observations, Texas researchers further found that pyruvate-dihydroxyacetone supplementation improved the insulin sensitivity of insulin resistant rats and reduced plasma cholesterol levels induced by a high cholesterol diet as well as lowered blood pressure and heart rate in obese individuals.  Pyruvate may be used as anti-toxic agent for neural protection. Because zinc neurotoxicity is likely one of the key mechanisms of ischemic brain injury, Korean researchers tested the beneficial effects of pyruvate on