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How much nicotine remains in the NicoDerm CQ® patch after 24 hours of use?

April 26, 2017hours NicoDerm nicotine patch remains

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How much nicotine remains in the NicoDerm CQ® patch after 24 hours of use?

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The rate of delivery of nicotine to the patient from each system (40 ug/cm2/h) is proportional to the surface area. About 73% of the total amount of nicotine remains in the system after 24 hours of application. NicoDerm CQ’s systems are labeled by the dose actually absorbed by the patient. The dose of nicotine absorbed from the NicoDerm system represents 68% of the amount released in 24 hours. The other 32% (e.g., 9 mg/day for the 21 mg/day system) volatilizes from the edge of the system.