How well are the active ingredients of Xandrox15-PLUS absorbed into the dermis of the scalp?
A. Ethyl alcohol is one of the few substances that freely permeates the skin (the permeability coefficient of ethanol across human skin in 8 x 10 –8 mol/cm2) and it transports the minoxidil, azelaic acid and finasteride with it. The penetration enhancing effects of ethanol play a significant role in minoxidil absorption. The effective absorption of topical minoxidil and finasteride depends on the vehicle composition. Greater effects are achieved when the fraction of the volatile component increases, especially at ethanol concentrations higher than 50% (and maximizing at 90%).