How well does the EndoPAT™ correlate with conventional cardiovascular risk factors (Framingham Risk Score)?
Since 2003 the Framingham Heart Study has included endothelial function measurements with EndoPAT™. All three study cohorts (the original study population, the Offspring and the 3rd generation cohort) have been tested with EndoPAT™, totaling over 5,000 subjects. A crosssectional analysis of 1,957 3rd Generation subjects was published in movement (May 2008) by Hamburg et al.(9) The study demonstrated a significant inverse relation between EndoPAT™ index and multiple CV risk factors, including: male sex, body mass index, total/HDL cholesterol, diabetes, smoking and lipid-lowering treatment. For more information about the correlation between the EndoPAT™ and traditional Risk Factors please refer to the product overview page 6. (9) Hamburg NM, Keyes MJ, Larson MG, Vasan RS, Schnabel R, Pryde MM, Mitchell GF, Sheffy J, Vita JA, Benjamin EJ Cross-Sectional Relations of Digital Vascular Function to Cardiovascular Risk Factors in the Framingham Heart Study.
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