I am about to begin receiving zoledronic acid to help with bone pain and to strengthen my bones. What are its side effects?
About 25 percent of patients can get a flulike illness after the first infusion (fever, bone, and muscle aches). Kidney function can be adversely affected by this drug. There have been a number of cases of death of bone in the jaw (osteonecrosis of the jaw) that have implicated zoledronic acid as a possible cause. Low blood calcium levels can occur as a result of the administration of this drug, but can be prevented by taking calcium and vitamin supplements. How can the side effects of Zometa® (zoledronic acid) be prevented? Question: I am about to begin zoledronic acid to help with bone pain and to strengthen my bones. Is there anything I can do to prevent any side effects? Answer: Premedications, such as Tylenol or nonsteroidal antiinflammatory drugs, can be given before the first administration of zoledronic acid to prevent the flulike syndrome. Kidney function tests need to be checked before each administration of zoledronic acid so that the dose can be modified or withheld if ther
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