I am not sure how to frame the research question or how to articulate the specific aims for the type of project called for in this RFA (i.e., tool development). Can you provide any guidance?
With respect to framing the research question, you should begin by describing the state of the current methodology/technology used to address particular types of research questions. Demonstrate the shortcomings of current approaches and describe what tool you will develop to fill the gap. Explain how what you will develop will improve on existing methodologies or technologies. Then identify types of research questions that future researchers could address using your tool (or how using your tool to address these research questions would be easier or result in improved data quality or interpretation). With regard to specific aims, they should directly relate to the methodology or technology you are developing and its validation.
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