I heard that progesterone cream is a natural way for postmenopausal women to build bone. What is it and is it safe?
Progesterone cream is an irregularly absorbed form of progestin. The amount of progestin absorbed varies greatly between individuals. Very few studies indicate that progestin has a potent effect on bone at all. There is absolutely no fracture data available. In addition, there are no good clinical trials that can tell us whether progesterone cream is safe for bone or safe for the uterus if used along with estrogen therapy. In summary, progesterone cream is not recommended for the prevention or treatment of osteoporosis. And furthermore, progesterone cream is not recommended as a means to protect the uterus.