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If a child receives a birth dose of Hepatitis B vaccine, and then Pediarix at 2 months and 8 months, does there need to be an eight week interval between the 2 and 3 dose of Pediarix?

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If a child receives a birth dose of Hepatitis B vaccine, and then Pediarix at 2 months and 8 months, does there need to be an eight week interval between the 2 and 3 dose of Pediarix?

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You need to make sure that the minimum spacing intervals are observed for every antigen in the vaccine (except for those for which the series is already complete). In this specific case, the child is already complete for Hepatitis B and is late for the 3rd dose of DTaP and Hib. Since the minimum interval for dose 2 and dose 3 of Pediarix (per the package insert) is six weeks, six weeks would seem to be an acceptable interval in this situation.

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