If a compound has the same mass as a substrate or product, does this interfere with RapidFire® analysis?
We use the highly selective MRM mode of triple quadrupole mass spectrometry to perform analyte quantitation. Thus, in order for a compound to interfere with RapidFire® quantitation it has to have the same mass as one of the analytes and also produce the same fragment upon dissociation within the mass spec. Whilst this is theoretically possible, in practice it happens extremely rarely.