Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

If a compound has the same mass as a substrate or product, does this interfere with RapidFire® analysis?

0
Posted

If a compound has the same mass as a substrate or product, does this interfere with RapidFire® analysis?

0

We use the highly selective MRM mode of triple quadrupole mass spectrometry to perform analyte quantitation. Thus, in order for a compound to interfere with RapidFire® quantitation it has to have the same mass as one of the analytes and also produce the same fragment upon dissociation within the mass spec. Whilst this is theoretically possible, in practice it happens extremely rarely.

What is your question?

*Sadly, we had to bring back ads too. Hopefully more targeted.