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If an 18-year-old presents for meningococcal vaccine with a history of a reaction to diphtheria toxoid, should we administer MPSV4 instead of MCV4?

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If an 18-year-old presents for meningococcal vaccine with a history of a reaction to diphtheria toxoid, should we administer MPSV4 instead of MCV4?

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It depends on the reaction. If it was an anaphylactic type reaction, then give MPSV4. If it was an Arthus reaction and at least 10 years have elapsed, you can give MCV4.

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