If I vaccinate my pullet flocks with Clostridium perfringens type A toxoid, do I still need to use water acidifiers, probiotics, enzymes and prebiotics to keep my antibiotic-free flocks free from NE?
There are no known conflicts for the concomitant use of Clostridium perfringenstype A toxoid and other non-antibiotic products for the control of NE. Most alternative compounds do not have a specific claim or direct effect on the incidence or severity of clinical and subclinical NE. Instead, they alter the profile of gut micro flora by limiting the colonization of unfavorable bacteria while promoting the growth of more favorable species. Strategic use of these alternative compounds may help optimize growth, provided they are used in a manner that complements their modes of action. Clostridium perfringens type A toxoid, on the other hand, provides specific protection via passive maternal antibodies against the alpha-toxin produced by C. perfringens types A and C and, therefore, can be used as an aid in the control of NE caused by these bacteria.
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