In the absence of patient-oriented evidence, might this information be useful in clinical decision-making?
Much of medical knowledge is still lacking in terms of patient-oriented outcomes research. Clinical decisions based on extrapolated disease-oriented evidence are not proven to be appropriate. However, clinicians still need to make decisions in situations where patient-oriented evidence is not yet available. Disease-oriented evidence is considered relevant for DynaMed in situations where patient-oriented evidence is lacking. Individual clinicians will have to determine if this information is considered relevant within their practice. When disease-oriented evidence is not presented as such in the supporting reference, DynaMed commentary will be added and may appear as “patient-oriented outcomes not assessed”, “clinical outcomes not assessed”, or specific commentary pointing out problems with extrapolating the information to clinical care. 3. Is this information part of a clinical controversy? In situations where the evidence does not clearly support or refute a clinical fact, opposing vi
