Is a bicuspid aortic valve a risk factor for adverse outcome after an autograft procedure?
GROUND: Recently, bicuspid aortic valve disease is posed to be a possible risk factor for dilatation of the pulmonary autograft. METHODS: Analysis of all 123 patients in our prospective cohort with their native aortic valve in situ at the autograft procedure. RESULTS: The bicuspid aortic valve group (n = 81) had more males (p = 0.05), prior cardiac surgery (p = 0.02), prior aortic valve balloon dilatation (p = 0.01), aortic stenosis (p = 0.03), and less deterioration of left ventricular function (p = 0.02) than the tricuspid group (n = 42). Hospital mortality occurred in 3 patients (bicuspid 2, tricuspid 1). The follow-up was 99% complete (median, 5.3 years; SD, 3.5; range, 0.1 to 13.4) with a total of 674 patient years. During follow-up 4 patients died (bicuspid 2, tricuspid 2). Overall survival was 95% (95% confidence interval [CI], 89% to 98%) at 5 and 10 years. Seven patients required reoperation for autograft failure, all structural. Freedom from autograft reintervention was 97% (
