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Is bone marrow trephine biopsy always mandatory in staging Hodgkins disease?

April 26, 2017biopsy bone disease hodgkin mandatory marrow staging trephine

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Is bone marrow trephine biopsy always mandatory in staging Hodgkins disease?

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E Cavalieri, AP Anselmo, V Gianfelici, N Frattarelli, E Pescarmona, R Foa, and A Pulsoni We reviewed data from 690 adult patients with Hodgkin’s disease (HD) to determine whether bone marrow trephine biopsy (BMTB) is mandatory for all patients. The data suggest that it is not necessary in clinical stage I-IIA. However, bilateral BMTB is recommended in the presence of B symptoms also in patients with localized stage disease.