Is high fructose corn syrup metabolized differently than other sweeteners?
No. The myth that high fructose corn syrup is metabolized differently than other caloric (nutritive) sweeteners is based on studies that looked at pure fructose, not the mixture of fructose and glucose found in high fructose corn syrup. The most recent metabolic research published in the February 2007 edition of Nutrition found “no differences in the metabolic effects” of high fructose corn syrup and sucrose on circulating levels of glucose, leptin, insulin and ghrelin in a study group of lean women.
