Is it OK to Split my Dose of Gleevec?
Novartis Oncology One Health Plaza East Hanover, NJ 087939-1080 March 11, 2008 Dear Dr. Porto: This letter is in response to your request for information regarding GleevecĀ® (imatinib mesylate). As long as the full daily dose is consumed, there are no problems anticipated in taking Gleevec 2-4 times a day. Anecdotally, taking a 400 mg or 600 mg daily dose on a BID basis seems to decrease GI distress. It is important, however, that patients remember to take all doses, and with a full glass of water and after food. Thank you for your interest in Novartis Oncology.