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Is it possible to “plate” cryopreserved human hepatocytes?

April 26, 2017cryopreserved hepatocytes Human plate possible

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Is it possible to “plate” cryopreserved human hepatocytes?

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IVT now offers plateable cryopreserved human hepatocytes. Please refer to the characterization tables to find the lots that show excellent plating efficiency. Contact IVT to inquire about purchasing these cells.

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A. No. While cryopreserved hepatocytes retain substantial drug metabolism capability, they generally lose the ability to attach to common substrates such as collagen. BD Gentest now offers particular lots which have been specifically tested for the ability to replate and to induce after cryopreservation. The Catalog Nos. are 454550 and 454551.