AmealPeptide® is produced from nonfat milk. Since 1997, Calpis has sold more than 250 million doses of AmealPeptide® in Japan. We have not received any reports of side effects. Our clinical study data show that patients who take AmealPeptide® along with their hypertension medications gained further lowering benefits. This could lead you to take a lower dose of hypertension medication, meaning fewer side effects.