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Is it safe to breastfeed following methotrexate?

breastfeed methotrexate safe
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Is it safe to breastfeed following methotrexate?

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The advice given to mothers who are taking regular oral doses of methotrexate, not for an ectopic pregnancy but to treat another entirely different condition, is NOT to breastfeed during their treatment. Methotrexate is excreted into breast milk in low concentrations. The significance of this is not yet known. However, because the drug may accumulate in neonatal tissues, breast feeding is not recommended in long-term use of methotrexate. The American Academy of Paediatrics considers methotrexate to be contraindicated during breast feeding because of several potential problems, including immune suppression, neutropenia, adverse effects on growth, and carcinogenesis. HOWEVER, the advice for women who have had Methotrexate for the treatment of ectopic pregnancy is different. In this case, Methotrexate is usually given as a one off dose (or occasionally two doses) by injection into a large muscle. It antagonises folic acid (vitamin B9) and causes it to be excreted, depleting the body of th

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