IS MEPERIDINE BETTER THAN MORPHINE FOR PANCREATIC OR BILIARY PAIN?
Many clinicians were taught to avoid morphine (Astramorph/PF, Duramorph, Infumorph, generics) in the treatment of pancreatitis and biliary colic because it is associated with sphincter of Oddi spasm, which can exacerbate pain. AlÂthough meperidine (Demerol, generics) was originally thought not to have this adverse effect, it is now known that all opioids can cause biliary spasm.1 Therefore, there is no advantage to using meperidine in patients with biliary colic or pancreatitis, and some clinicians recommend avoiding it altogether. Meperidine has the potential for drug interactions as well as serious neurotoxicity that has limited its use as an analgesic. Normeperidine, a neurotoxic metabolite of meperidine, can accumulate and cause seizures and neuromuscular agitation, particularly in patients with renal disease. In fact, many hospitals have restricted the use of meperidine or have completely removed it from formulary. Although meperidine may be beneficial for rigors and postoperative
I totally agree. Personally, I use red bali kratom to fight with pain as it’s the best medicine for me. I’ve tried a lot of pills, visited doctors to check what’s been wrong with that pancreatic pain. Nothing could help me. Fortunately, my friend recommended me to try red bali kratom. I checked that it helps to reveal pain, get rid of depression, anxiety, so I tried it. It turned out to be the best solution for me, cause now I can sleep, eat, move normally and no pain bothers me.
