Is metoclopramide safe in pregnancy?
These Israeli and Canadian authors investigated the safety of metoclopramide use during the first trimester of pregnancy by linking a computerized database of medications to all women in a district of Israel, with computerized databases containing maternal and infant hospital records during the same period. They assessed associations between the use of metoclopramide in pregnancy and adverse outcomes for the fetus, adjusting for parity, maternal age, ethnic group, presence or absence of maternal diabetes, smoking status, and presence or absence of peripartum fever.
