Is there a pattern of inheritance for specific alterations in the BRCA1 gene?

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Is there a pattern of inheritance for specific alterations in the BRCA1 gene?

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A large number of different alterations has been identified in the BRCA1 gene. For the most part, each BRCA1 family carries a particular, characteristic alteration. Recently, Canadian and U.S. scientists identified one particular alteration in several families with multiple cases of breast, or breast and ovarian cancers. These high-risk families were all from an Ashkenazi Jewish background, with roots in Eastern Europe. So far, information from 10 such families is published in the scientific literature. This particular alteration is named 185delAG. Two adjacent pairs of DNA subunits (nucleotides) are missing in the altered gene. This alteration, which is like taking two letters out of one word in a long book chapter, causes the cell to shorten its translation of the gene’s usual instructions for making a protein. At the present time, scientists do not know the function of the protein encoded by the normal gene. 7. What is the finding of the National Institutes of Health study which app