Is there an increased risk of breast cancer and abnormal mammograms in women taking estrogen alone (without progestin) or other E+P formulas?
The current report addresses only the issue of E+P use in the form of pills. Final results from the ongoing Estrogen-Alone (E-Alone) study are unknown at this time. Importantly, the WHI investigators have been told that, as of May 31, 2002, no increase in breast cancer has been seen in the E-alone WHI trial. Participants in the E-Alone study are asked to continue to take their study pills and to come for their regular clinic visits. The National Heart, Lung, and Blood Institute, which oversees WHI, continues to review the study for women receiving E-Alone, and they will provide investigators and participants with any new information about the study that might affect their participation This information has been superceded by the 2004 Hormone Program Update.