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Is there any way to reduce the frequency of refills required?

April 26, 2017Frequency reduce refills

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Is there any way to reduce the frequency of refills required?

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If the patient is receiving a low concentration of the drug, the frequency of refills can be reduced by increasing the drug concentration. Preservative-free morphine sulfate is commercially available in 10 mg/mL and 25 mg/mL concentrations. However, drug concentrations should never be more than 10 times the daily dose, and drug stability requirements should not be exceeded. The drug stability (defined as >90% of the initial concentration) for morphine sulfate is 180 days.