Is this the first large cohort study of cancer survivors to look for genetic consequences of curative treatments?
There has been one large-scale study of genetic conditions among the offspring of childhood cancer survivors conducted by the National Cancer Institute. The number of subjects was only a quarter of those enrolled in the GCCT and the cancer treatments were different then they are today because the study was conducted such a long time ago. A pilot study of the offspring of survivors of childhood cancer in Denmark has also been conducted which proved the feasibility of the current effort (see the Publications list). 7. How are participants selected for the study? Cancer survivors under the age of 35 were chosen for study. For children with cancer it was required that they live to at least 15 years of age and have the possibility to have children of their own. Cancer survivors were identified from the national cancer registries of Denmark and Finland. Population registries were used to identify the offspring of these cancer survivors. Population registries were also used to identify the si
