Long term stability of stocked KI03?
Jerome A. Halperin, Executive Vice President-CEO of The United States Pharmacopeial Convention, Inc., wrote to the Chairman of the U.S. Nuclear Regulatory Commission on January 30, 1998 of a recent assay of ‘expired’ KI03 tablets. The Thyro-Block Tablets (Potassium Iodate Tablets, USP, Lot T242N, Exp. November 89), after the USP Drug Research and Testing Laboratory analyzed samples, showed that approximately 11 years after their manufacture and eight years after their expiry date, the tablets assayed at 99.1% of the labeled content of Potassium Iodate. (This result was well within the rubric range of 92.5 to 107.5% required by the monograph.) (Mr. J. Halperin should know what he is talking about. In 1979, while deputy director of the Bureau of Drugs of the Food and Drug Administration, he had directed the effort to get Potassium Iodate Solution, USP, manufactured and stockpiled in Harrisburg, Pennsylvania during the Three Mile Island incident!) Also, in conversations with one of the la
