May tobacco dependence medications be used long-term (e.g., 6 months or more)?

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May tobacco dependence medications be used long-term (e.g., 6 months or more)?

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Yes. This approach may be helpful with smokers who report persistent withdrawal symptoms during the course of pharmacotherapy or who desire long-term therapy. A minority of individuals who successfully quit smoking use over-the-counter nicotine replacement medications (gum, nasal spray, inhaler) long-term. The use of these medications long-term does not present a known health risk. Additionally, the FDA has approved the use of bupropion SR for a long-term maintenance indication.