My pathology report showed follicular variant of papillary thyroid cancer-how does this differ from regular papillary thyroid cancer?
The two most common types of well differentiated thyroid cancer are papillary and follicular cancer. Very commonly, when the tumor is examined under the microscopic, there are mixed features of different cell types seen, with elements of both papillary and follicular tumor types seen in the same tumor. There is little evidence that mixed follicular variant papillary cancer carries a significantly different connotation compared to simple papillary thyroid cancer. See Pure versus follicular variant of papillary thyroid carcinoma. Cancer. 2003 Mar 1;97(5):1181-5. and Follicular Variant of Papillary Thyroid Carcinoma: A Comparative Study of Histopathologic Features and Cytology Resutls in 141 Patients. Endocr Pract. 2001 Mar;7(2):79-84. However in some studies, the behavior of this type of tumor may be slightly more aggressive compared to PTC alone Follicular variant of papillary thyroid carcinoma: clinical-pathological characterization and long-term follow-up. Cancer J. 2006 Jul-Aug;12(4)
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