My patient has diabetes and is controlling his blood pressure with lisinopril. Should he switch therapies to diuretics?
The 10% advantage for the diuretic in ALLHAT for cardiovascular disease and 20% advantage for heart failure were virtually identical among diabetic and non-diabetic participants. Therefore, a diuretic should be substituted for lisinopril or should be added if there are clear indications to continue the lisinopril.