RESTASIS ® Ophthalmic Emulsion contains cyclosporine. How does this affect the safety profile of RESTASIS ® ?
RESTASIS ® Ophthalmic Emulsion has a favorable safety profile. In fact, in clinical studies, there was no increase in infection, interaction with other drugs, increase in intraocular pressure, or detectable systemic drug absorption in the blood for up to 12 months of treatment. The delivery vehicle for cyclosporine in RESTASIS ® is a unique, oil-based ophthalmic emulsion. This emulsion technology provides effective drug delivery to ocular tissue and is effective with a very low cyclosporine concentration (0.05%).