Should individuals who have been exposed to hemorrhagic fever viruses receive postexposure prophylaxis?
Currently, there is no recommended postexposure prophylactic therapy for individuals exposed to hemorrhagic fever viruses. High-risk and close contacts of patients with viral hemorrhagic fever and individuals with a direct exposure to hemorrhagic fever viruses should be placed on fever watch for 21 days after exposure. If fever (≥ 101º F) develops, ribavirin should be initiated as soon as possible if the pathogen is susceptible to therapy. References: Borio L, Inglesby T, Peters CJ, et al. Hemorrhagic fever viruses as biological weapons. Medical and public health management. JAMA 2002;287:2391-405.