The fourth edition of TNM included a classification for brain tumours. Why has this been left out of the fifth and sixth editions?
The application of TNM to CNS tumours has not been successful. This particularly concerns the classification as a predictor of outcome. That carries little weight compared with other factors such as histological type, tumour location and patient age. The N does not apply at all, and the M rarely plays a role. This field is still under study to find other means of classifying CNS tumours that will carry prognostic significance. Further details may be obtained from the 6th edition AJCC Cancer Staging Manual [1] and from Ohgaki et al. 2001 [7]. 1.13 Classification of primary peritoneal neoplasms How do you classify primary neoplasms of the peritoneum? We did not find any TNM classification for these tumours. Some of our colleagues use the FIGO/TNM ovary classification. Because of the rarity of primary peritoneal neoplasms, there is indeed no TNM classification for them. Basically, there are two primary peritoneal entities: mesothelioma and primary carcinoma of the peritoneum. The latter,
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- The fourth edition of TNM included a classification for brain tumours. Why has this been left out of the fifth and sixth editions?
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