We have a patient on EURAMOS 1 who should be having surgery this week but not sure if this is going to go ahead. Should we be giving additional methotrexate if surgery is delayed?

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We have a patient on EURAMOS 1 who should be having surgery this week but not sure if this is going to go ahead. Should we be giving additional methotrexate if surgery is delayed?

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Patients should have no more than six courses of methotrexate (MTX) administered before surgery to be eligible for randomization. If the patient has already had 4 courses of MTX (i.e. in cycle 1 and 2) then another 2 courses of MTX could be given before surgery. If given, this additional MTX should be recorded on the Chemotherapy form for cycle 2 (questions 14-16 should be answered).

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