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What are a couples chances of having a child with Downs Syndrome?

child Couple Down's syndrome
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What are a couples chances of having a child with Downs Syndrome?

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In the usual circumstance, the chances depend upon the age of the mother. Many studies were conducted on this and the odds of having a child with Down’s Syndrome at age 35 are approximately 1 in 350. Under age 25, the odds are about 1 in 1400 and at age 40 the odds are about 1 in 100. The chances of a parent of a child with Trisomy 21 having another child with Down’s Syndrome is approximately 1 in 100. If the child has a translocation, the recurrence risk can be as high as 100% or as low as 2%. Parents of children with translocation type of Down’s Syndrome should have chromosome analysis to detect a carrier state.

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